The best Side of stem cell clinic
Smaller-molecule inhibitors in the serine dipeptidases DPP8 and DPP9 (DPP8/nine) induce a lytic kind of cell Dying called pyroptosis in mouse and human monocytes and macrophages1,2. In mouse myeloid cells, Dpp8/9 inhibition activates the inflammasome sensor Nlrp1b, which subsequently activates pro-caspase-1 to mediate cell death3, but the mechanism